Zinc Chloride-Promoted Aryl Bromide− Alkyne Cross-Coupling Reactions at Room Temperature

…, EC Elleby, MJ Boyd, H Weissman…

文献索引：Finke, Aaron D.; Elleby, Eric C.; Boyd, Michael J.; Weissman, Haim; Moore, Jeffrey S. Journal of Organic Chemistry, 2009 , vol. 74, # 22 p. 8897 - 8900

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被引用次数: 49

摘要

Substoichiometric amounts of ZnCl2 promote the room temperature, Pd/P (t-Bu) 3-catalyzed cross-coupling of aryl bromides with alkynes. Pd (I) dimer 1 is demonstrated to be a particularly active precatalyst for this reaction. The reaction is general for a wide variety of aryl bromides.