Organic letters

Fragmentation of carbonyl oxides by N-oxides: An improved approach to alkene ozonolysis

C Schwartz, J Raible, K Mott, PH Dussault

文献索引：Schwartz, Chris; Raible, Joseph; Mott, Kyle; Dussault, Patrick H. Organic Letters, 2006 , vol. 8, # 15 p. 3199 - 3201

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被引用次数: 52

摘要

Ozonolysis of alkenes in the presence of amine N-oxides results in the direct formation of aldehydes. This reaction, which appears to involve an unprecedented trapping and fragmentation of the short-lived carbonyl oxide intermediates, avoids the hazards associated with generation and isolation of ozonides or other peroxide products.