Topological study of mechanistic diversity in conjugated fatty acid biosynthesis

P Bhar, DW Reed, PS Covello…

文献索引：Bhar, Palash; Reed, Darwin W.; Covello, Patrick S.; Buist, Peter H. Angewandte Chemie - International Edition, 2012 , vol. 51, # 27 p. 6686 - 6690

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被引用次数: 2

摘要

Plant-derived seed oils are of current interest in the context of renewable hydrocarbon-type industrial feedstocks.[1, 2] Functionalization of oleochemicals adds value to this commodity and is achieved by a set of O2-dependent, non-heme diiron enzymes known as desaturases.[3–5] The FAD2 subfamily is particularly interesting because of the mechanistic diversity exhibited by this set of sequence-related membrane proteins (Scheme 1).