Organocatalysis with proline derivatives: improved catalysts for the asymmetric Mannich, nitro-Michael and aldol reactions
…, DM Shaw, DA Longbottom, JB Gold, SV Ley
文献索引：Cobb, Alexander J. A.; Shaw, David M.; Longbottom, Deborah A.; Gold, Johan B.; Ley, Steven V. Organic and Biomolecular Chemistry, 2005 , vol. 3, # 1 p. 84 - 96
The search for asymmetric catalysts that provide high yields and enantioselectivities is an on-going quest for organic chemists. An important area that has been intensively studied over the past few years is that of asymmetric organocatalysis, the primary advantage of which is that it avoids the use of metals, which can be both expensive and toxic. Proline 1 is one example of a versatile organocatalyst, which despite having been used effectively in the Hajos– ...
