Synthesis of N, N'-di (2-hydroxybenzyl) ethylenediamine-N, N'-diacetic acid (HBED) and derivatives

AE Martell, RJ Motekaitis, ET Clarke…

文献索引：Martell, Arthur E.; Motekaitis, Ramunas J.; Clarke, Eric T.; Harrison, J.J. Canadian Journal of Chemistry, 1986 , vol. 64, p. 449 - 456

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被引用次数: 26

摘要

Two synthetic approaches for the synthesis of N, N'-di (2-hydroxybenzyl) ethylenediamine-N, N'-diacetic acid (HBED) and derivatives are reported. The first involves conversion of N, N'-di (2-hydroxybenzyl) ethylenediamine to the diamide HBEDDA via reaction with formaldehyde and HCN followed by hydrolysis. Analysis of the species distribution curves of the Cu (II) chelates of N, N'-di (2-hydroxybenzyl) ethylenediamine-N, N'-diacetic acid (HBED) and its ...