Ex situ generation of stoichiometric and substoichiometric 12CO and 13CO and its efficient incorporation in palladium catalyzed aminocarbonylations

P Hermange, AT Lindhardt, RH Taaning…

文献索引：Elmore, Charles S.; Dean, Dennis C.; Melillo, David G. Journal of Labelled Compounds and Radiopharmaceuticals, 2000 , vol. 43, # 11 p. 1135 - 1144

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被引用次数: 160

摘要

... Journal of the American ... The ex situ generated CO and the two-chamber system were tested in the synthesis of several compounds of pharmaceutical interest and all of them were labeled as their [ 13 C]carbonyl counterparts in good to excellent yields based on limiting CO. ...

~82%

Atorvastatin, an HMG??COA reductase inhibitor and efficient ...

[Woo, Peter W. K.; Hartman, Jon; Huang, Yun; Nanninga, Thomas; Bauman, Kelvin; Butler, Donald E.; Rubin, John R.; Lee, Helen T.; Huang, Che C. Journal of Labelled Compounds and Radiopharmaceuticals, 1999 , vol. 42, # 2 p. 121 - 127]