... Please enable JavaScript to use all the features on this page. European Journal of Medicinal Chemistry. ... 1 H NMR (CDCl 3 ) δ ppm: 1.39(s, 9H), 1.48(br, s, 3H), 1.65(br, s, 3H), 3.74(s, 3H), 4.11(dd, J = 8.5 and 8.1 Hz, 1H), 4.35(dd, J = 8.5 and 3.5 Hz, H), 4.47(m, H). ...