Amino acid derivatives with anticonvulsant activity.

R Paruszewski, M STRUPINska, JP Stables…

文献索引：Paruszewski; Strupinska; Stables; Swiader; Czuczwar; Kleinrok; Turski Chemical and Pharmaceutical Bulletin, 2001 , vol. 49, # 5 p. 629 - 631

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被引用次数: 30

摘要

A series of benzylamides of N-alkylated, N-acylated or free nine cyclic and one linear amino acids as potential anticonvulsants have been synthesized. The structures of the obtained compounds were designed on the basis of the previously determined structure and physicochemical properties/anticvonvulsant activity relationship of the formerly synthesized compounds of this type. The obtained compounds were evaluated in mice after ...