Preparation of 5-(2-Methoxy-4-nitrophenyl) oxazole: A Key Intermediate for the Construction of VX-497

RJ Herr, DJ Fairfax, H Meckler…

文献索引：Kloc, Krystian; Mlochowski, Jacek; Mhizha, Sungano Synthetic Communications, 1997 , vol. 27, # 23 p. 4049 - 4057

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被引用次数: 18

摘要

... Volume: Page: ... Recently a program was carried out to develop a synthetic route for the multigram scale preparation of the hepatitis C drug candidate VX-497 (3, merimepodib), which is currently in phase II clinical research trials for the selective inhibition of ...