Integration of enabling methods for the automated flow preparation of piperazine-2-carboxamide

…, C Battilocchio, JM Hawkins, SV Ley

文献索引：Ingham, Richard J.; Battilocchio, Claudio; Hawkins, Joel M.; Ley, Steven V. Beilstein Journal of Organic Chemistry, 2014 , vol. 10, p. 641 - 652

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被引用次数: 22

摘要

Abstract Here we describe the use of a new open-source software package and a Raspberry Pi® computer for the simultaneous control of multiple flow chemistry devices and its application to a machine-assisted, multi-step flow preparation of pyrazine-2-carboxamide–a component of Rifater®, used in the treatment of tuberculosis–and its reduced derivative piperazine-2-carboxamide.