前往化源商城

举例 :可输入Filippa Pettersson 或者 Cancer Res. 75(6) , 1102-12, (2015) 或者10.1002/anie.201600521

Efficacious, orally bioavailable thrombin inhibitors based on 3-aminopyridinone or 3-aminopyrazinone acetamide peptidomimetic templates

PEJ Sanderson, TA Lyle, KJ Cutrona…

文献索引：Journal of Medicinal Chemistry, , vol. 41, # 23 p. 4466 - 4474

全文：HTML全文

被引用次数: 106

摘要

... Journal of Medicinal ... Departments of Antiviral Research, Biological Chemistry, Drug Metabolism, Medicinal Chemistry, Molecular Design and Diversity, and ... 4474. DOI: 10.1021/jm980368v. Publication Date (Web): October 9, 1998. Copyright © 1998 American Chemical Society. ...

(5-CHLORO-6-METHYL-2-OXO-3-PHENETHYLAMINO-2H-PYRAZIN-1-YL)-ACETIC ACID BENZYL ESTER结构式

(5-CHLORO-6-MET...

~%

N-[(6-amino-2-methylpyridin-3-yl)methyl]-2-[6-methyl-2-oxo-3-(2-phenylethylamino)pyrazin-1-yl]acetamide结构式

N-[(6-amino-2-m...

Efficacious, orally bioavailable thrombin inhibitors based o...

[Sanderson, Philip E. J.; Lyle, Terry A.; Cutrona, Kellie J.; Dyer, Dona L.; Dorsey, Bruce D.; McDonough, Colleen M.; Naylor-Olsen, Adel M.; Chen, I.-Wu; Chen, Zhongguo; Cook, Jacquelynn J.; Cooper, Carolyn M.; Gardell, Stephen J.; Hare, Timothy R.; Krueger, Julie A.; Lewis, S. Dale; Lin, Jiunn H.; Lucas Jr., Bobby J.; Lyle, Elizabeth A.; Lynch Jr., Joseph J.; Stranieri, Maria T.; Vastag, Kari; Yan, Youwei; Shafer, Jules A.; Vacca, Joseph P. Journal of Medicinal Chemistry, 1998 , vol. 41, # 23 p. 4466 - 4474]

Efficacious, orally bioavailable thrombin inhibitors based o...

[Sanderson, Philip E. J.; Lyle, Terry A.; Cutrona, Kellie J.; Dyer, Dona L.; Dorsey, Bruce D.; McDonough, Colleen M.; Naylor-Olsen, Adel M.; Chen, I.-Wu; Chen, Zhongguo; Cook, Jacquelynn J.; Cooper, Carolyn M.; Gardell, Stephen J.; Hare, Timothy R.; Krueger, Julie A.; Lewis, S. Dale; Lin, Jiunn H.; Lucas Jr., Bobby J.; Lyle, Elizabeth A.; Lynch Jr., Joseph J.; Stranieri, Maria T.; Vastag, Kari; Yan, Youwei; Shafer, Jules A.; Vacca, Joseph P. Journal of Medicinal Chemistry, 1998 , vol. 41, # 23 p. 4466 - 4474]

Efficacious, orally bioavailable thrombin inhibitors based o...

[Sanderson, Philip E. J.; Lyle, Terry A.; Cutrona, Kellie J.; Dyer, Dona L.; Dorsey, Bruce D.; McDonough, Colleen M.; Naylor-Olsen, Adel M.; Chen, I.-Wu; Chen, Zhongguo; Cook, Jacquelynn J.; Cooper, Carolyn M.; Gardell, Stephen J.; Hare, Timothy R.; Krueger, Julie A.; Lewis, S. Dale; Lin, Jiunn H.; Lucas Jr., Bobby J.; Lyle, Elizabeth A.; Lynch Jr., Joseph J.; Stranieri, Maria T.; Vastag, Kari; Yan, Youwei; Shafer, Jules A.; Vacca, Joseph P. Journal of Medicinal Chemistry, 1998 , vol. 41, # 23 p. 4466 - 4474]

Efficacious, orally bioavailable thrombin inhibitors based o...

[Sanderson, Philip E. J.; Lyle, Terry A.; Cutrona, Kellie J.; Dyer, Dona L.; Dorsey, Bruce D.; McDonough, Colleen M.; Naylor-Olsen, Adel M.; Chen, I.-Wu; Chen, Zhongguo; Cook, Jacquelynn J.; Cooper, Carolyn M.; Gardell, Stephen J.; Hare, Timothy R.; Krueger, Julie A.; Lewis, S. Dale; Lin, Jiunn H.; Lucas Jr., Bobby J.; Lyle, Elizabeth A.; Lynch Jr., Joseph J.; Stranieri, Maria T.; Vastag, Kari; Yan, Youwei; Shafer, Jules A.; Vacca, Joseph P. Journal of Medicinal Chemistry, 1998 , vol. 41, # 23 p. 4466 - 4474]

Efficacious, orally bioavailable thrombin inhibitors based o...

[Sanderson, Philip E. J.; Lyle, Terry A.; Cutrona, Kellie J.; Dyer, Dona L.; Dorsey, Bruce D.; McDonough, Colleen M.; Naylor-Olsen, Adel M.; Chen, I.-Wu; Chen, Zhongguo; Cook, Jacquelynn J.; Cooper, Carolyn M.; Gardell, Stephen J.; Hare, Timothy R.; Krueger, Julie A.; Lewis, S. Dale; Lin, Jiunn H.; Lucas Jr., Bobby J.; Lyle, Elizabeth A.; Lynch Jr., Joseph J.; Stranieri, Maria T.; Vastag, Kari; Yan, Youwei; Shafer, Jules A.; Vacca, Joseph P. Journal of Medicinal Chemistry, 1998 , vol. 41, # 23 p. 4466 - 4474]