Tetrahedron

Sequential one-pot method for oxy-Michael addition, Heck coupling, and degradation followed by condensation: facile synthesis of 2-benzoxepin-3 (1H)-ones

AGK Reddy, J Krishna, G Satyanarayana

文献索引：Reddy, A. Gopi Krishna; Krishna; Satyanarayana Tetrahedron, 2013 , vol. 69, # 47 p. 10098 - 10107

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被引用次数: 9

摘要

Abstract A sequential one-pot intermolecular oxy-Michael addition, intermolecular Heck coupling, and intramolecular degradation (retro-oxy-Michael addition) followed by condensation method has been developed for the synthesis of interesting 2-benzoxepin-3 (1H)-ones. Significantly, the 2-benzoxepin-3 (1H)-ones form the core quantum of biologically vital natural products. The initial oxy-Michael addition and Heck coupling steps involve a ...