Tetrahedron letters

Ti (III)-Mediated reductions of N-hydroxy imidazoles to 1-protio-2, 4 (5)-disubstituted derivatives

BH Lipshutz, MC Morey

文献索引：Lipshutz, Bruce H.; Morey, Matthew C. Tetrahedron Letters, 1984 , vol. 25, # 13 p. 1319 - 1320

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被引用次数: 9

摘要

... Abstract. N-hydroxy imidazoles are converted TiCl 3 in MeOH/H 2 O to N-protio derivatives, useful precursors of chiral amino acids. References. 1; Lipshutz, BH, Morey, MC, J. Am. Chem. Soc., in press. 2; BH Lipshutz, MC Morey; J. Org. Chem., 48 (1983), p. 3745. ... Some reagents included: Zn¦HCl, LAH, H 2 ,Pd¦C, Al(Hg), Na(Hg), Zn/¦HOAc, BH 3 THF. 5; JM McCall, RE TenBrink; Synthesis (1975), p. 335. ...