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Synthesis of 2-Thiocytosines and 2-Thiouracils

CW Whitehead, JJ Traverso

文献索引:Whitehead; Traverso Journal of the American Chemical Society, 1956 , vol. 78, p. 5294,5296

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被引用次数: 16

摘要

In previous the reactions of ureas with N-alkyl-and N-arylthioureas to give excellent ethoxymethylene derivatives of diethyl malonate, yields of 5-carbethoxy-2-thiouracils (11). Equally ethyl cyanoacetate and ethyl oxalacetate were good yields of 5-carbethoxy-2- thiocytosines (I11 j shown to yield carbethoxypyrimidines. In this and 5-cyano-2- thiocytosines (V) were obtained from present work, ethoxymethylene derivatives of this the ...