Phytochemistry

Incorporation of phenethylisoquinolines into colchicine in isolated seeds of Colchicum autumnale

A Nasreen, H Gundlach, MH Zenk

文献索引：Nasreen, Amber; Gundlach, Heidrun; Zenk, Meinhart H. Phytochemistry, 1997 , vol. 46, # 1 p. 107 - 115

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被引用次数: 16

摘要

The physiological parameters for application experiments using immature seeds of Colchicum autumnale were optimized, so that incorporation rates in the range of 10% and higher were consistently obtained with intermediate precursors. Application of tritium and 13C-labelled phenethylisoquinolines showed that N-methylation occurs prior to the substitution of ring C and that the free hydroxy group in position 13 of autumnaline is ...