Tetrahedron letters

A new synthetic route to 2-oxazolines. The electrochemical reduction of N-(2, 2-dichloroethyl) amides as a key step

A Guirado, R Andreu, J Gálvez

文献索引：Guirado, Antonio; Andreu, Raquel; Galvez, Jesus Tetrahedron Letters, 1998 , vol. 39, # 9 p. 1071 - 1074

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被引用次数: 16

摘要

A convenient new method for the synthesis of 2-oxazolines has been established involving the preparation of N-(2, 2-dichloroethyl) amides followed by electrochemical reductive cyclizations. It has been applied successfully in preparing previously unknown 4-alkylamino- 2-phenyl-2-oxazolines in fair to good yields.