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The Journal of organic chemistry

Efficient Suzuki-Miyaura coupling of (hetero) aryl chlorides with thiophene-and furanboronic acids in aqueous n-butanol

CA Fleckenstein, H Plenio

文献索引:Gronowitz,S.; Roos,C. Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1975 , vol. 29, p. 990 - 998

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被引用次数: 98

摘要

... Chem. ... Table 2, entry 5). Interestingly, when n-butanol was used as a solvent, the highly active 2-chloropyrimidine preferably underwent an S N Ar ... c Average of two runs, products were isolated via column-chromatography (silica (20 × 3 cm), cyclohexane:EtOAc:NEt 3 (10:1:1) as ...