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Synthesis and biological evaluation of β-D-pentofuranonucleoside derivatives of 2-azidoadenine and 6-azidopurines

C Mathé, T Lioux, G Gosselin

文献索引:Mathe, Christophe; Lioux, Thierry; Gosselin, Gilles Nucleosides, Nucleotides and Nucleic Acids, 2003 , vol. 22, # 5-8 p. 605 - 609

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被引用次数: 9

摘要

Abstract β-D-pentofuranonucleoside derivatives of 2-azidoadenine and 6-azidopurines have been synthesized. The azido-tetrazolo tautomerism observed on such nucleoside analogues has been studied. The compounds were tested for their activity against HIV and HBV but they did not show significant antiviral effect.