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A new and efficient total synthesis of streptonigrin

AS Kende, DP Lorah, RJ Boatman

文献索引:Kende, Andrew S.; Lorah, Dennis P.; Boatman, Rodney J. Journal of the American Chemical Society, 1981 , vol. 103, # 5 p. 1271 - 1273

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被引用次数: 45

摘要

0002-7863/8 1/1503-1 27 1 $01.25/0 have reported approaches to the synthesis of this polyfunctional molecule. 24 The first synthesis of its carbon framework was achieved in these laboratories in 1978, 3a and an imaginative total synthesis of streptonigrin in 0.013% yield in over 30 steps from 2-benzyloxy-3, 4-dimethoxybenzaldehyde was recently reported bv Weinreb and co-~ orkers.~ We now describe concurrent studies i; this area which have ...