Abstract Chiroptical properties of several 2 or 3 monosubstituted azetidines, pyrrolidines and piperidines as free bases and N-[2-pyridyl N-oxide] derivatives has been examined. The absolute configuration can be unambiguously established, independently on the nature of the substituent and the size of the ring, only for 2-substituted N-[2-pyridyl N-oxide] amine derivatives. This behaviour is explained in terms of limited rotational freedom in these ...
