Molecules

Synthesis and phytotoxic activity of new pyridones derived from 4-hydroxy-6-methylpyridin-2 (1H)-one

…, VM Moreira Valente, LC Almeida Barbosa, A Rathi…

文献索引：Demuner, Antonio Jacinto; Valente, Vania Maria Moreira; Barbosa, Luiz Claudio Almeida; Rathi, Akshat H.; Donohoe, Timothy J.; Thompson, Amber L. Molecules, 2009 , vol. 14, # 12 p. 4973 - 4986

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被引用次数: 14

摘要

Abstract Commercial dehydroacetic acid was converted into 4-hydroxy-6-methylpyridin-2 (1H)-one (3), which was then condensed with several aliphatic aldehydes to produce seven new title compounds in variable yields (35–92%). Reaction of 3 with α, β-unsaturated aldehydes resulted in the formation of condensed pyran derivatives 4g'and 4h'. A mechanism is proposed to explain the formation of such compounds. The effects of all ...