The Journal of organic chemistry

Solid-phase synthesis of 4 (1 H)-quinolone and pyrimidine derivatives based on a new Scaffold polymer-bound cyclic malonic acid ester

X Huang, Z Liu

文献索引：Huang, Xian; Liu, Zhanxiang Tetrahedron Letters, 2001 , vol. 42, # 43 p. 7655 - 7657

全文：HTML全文

被引用次数: 46

摘要

An efficient method for the preparation of polymer-bound cyclic malonic acid ester starting from Merrifield resin has been developed. Reaction of the resin-bound cyclic malonic acid ester with triethyl orthoformate and subsequent double substitution with nucleophilic