Panizzon3s4 has condensed 2-and 4-halopyridines with phenylEPcetonitrile in the presence of sodium amide but did not extend the reaction to the 3-isomer, presumably because of the well-recognized aromatic nature of the 3-position in the pyridine rmg. It has been found, however, that 3-bromopyridine is readily converted into a-phenyl-a-(3-pyridyl)- acetonitrile by this reaction. This was converted to 4-phenyl-4-(3-pyridy1)-6- ...
