Discovery of novel small molecule cell type-specific enhancers of NF-κB nuclear translocation

G Gong, Y Xie, Y Liu, A Rinderspacher, SX Deng…

文献索引：Gong, Gangli; Xie, Yuli; Liu, Yidong; Rinderspacher, Alison; Deng, Shi-Xian; Feng, Yan; Zhu, Zhengxiang; Tang, Yufei; Wyler, Michael; Aulner, Nathalie; Toebben, Udo; Smith, Deborah H.; Branden, Lars; Chung, Caty; Schuerer, Stephan; Vidovic, Dusica; Landry, Donald W. Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 4 p. 1191 - 1194

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被引用次数: 8

摘要

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... An IKKβ inhibitor reported to block NF-κB transcriptional activities in Jurkat T cells, was found to enhance NF-κB translocation in HUVEC cells. These studies suggested a noncanonical NF-κB signaling pathway independent of IKKβ in HUVEC cells. ... A reported IKKβ inhibitor to inhibit ...