Uridine 5'-diphosphate glucose analogs. Inhibitors of protein glycosylation that show antiviral activity

…, P Fernandez-Resa, MT Garcia-Lopez…

文献索引：Camarasa; Fernandez-Resa; Garcia-Lopez; De las Heras; Mendez-Castrillon; Alarcon; Carrasco Journal of Medicinal Chemistry, 1985 , vol. 28, # 1 p. 40 - 46

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被引用次数: 44

摘要

Nucleoside diphosphate sugars are intermediates that donate glycosyl residues in the biosynthesis of polysaccharides, glycolipids, glycoproteins, and some components of the bacterial cell wall. Compounds that interfere with protein glycosylation show a variety of biological such as inhibition of the replication of enveloped animal For instance, 2-deoxy-~- glucose is a glycosylation inhibitor having antiviral activity, Pg which is transformed to ...