Synthesis of 3, 5-dibenzyl-4-amino-1, 2, 4-triazole was accomplished via a conventional method as well as microwave irradiation method, followed by diazotization and coupling with 2, 4-pentanedione. The dinucleating ligand was isolated and complexed with Ni (II), Cu (II) and Ru (III) chlorides. These complexes were screened on Jurkat, Raji & PBMC cell lines for anticancer activity. Ruthenium complexes showed potential anticancer activities.
