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Synthesis and pharmacological evaluation of. alpha.-naphthylalkylamines

S Casadio, G Pala, T Bruzzese, C Turba…

文献索引:Casadio,S. et al. Journal of Medicinal Chemistry, 1970 , vol. 13, p. 418 - 421

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被引用次数: 0

摘要

Method B. 1, 5-Dimorpholino-3-(a-naphthy1) pentane (24).-Finely powdered SaNHs (31.2 g, 0.8 mol) was added portiotiwise to a vigorously stirred soliitiori of cu, or-bis (P- morpholiiioethyl)-liiaphthylacetoiiitl. ile (7S. 7 g, 0.2 mol) in dry xylene (600 ml). The mixture was refliixed for 30 hr with stirring mid cooled to room temperature, and then IT&\ vas caiitioiisly added. The organic. layer was separated, waihed with H20, and dried (NajS04). ...