Tetrahedron: Asymmetry

Asymmetric synthesis of (1R, 2S, 3R)-2-acetyl-4-(1, 2, 3, 4-tetrahydroxybutyl) thiazole

AT Ung, SG Pyne

文献索引：Ung, Alison T.; Pyne, Stephen G. Tetrahedron Asymmetry, 1998 , vol. 9, # 8 p. 1395 - 1407

全文：HTML全文

被引用次数: 23

摘要

(1R,2S,3R)-2-Acetyl-4(5)-(1,2,3,4-tetrahydroxybutyl)imidazole (THI) 1, a constituent of Caramel Colour III, has been found to depress blood lymphocyte counts in both mice and rats.[1]THI produces lymphopenia, apparently without toxic effects, in rats and mice and is able to affect the immune