A study and mechanistic interpretation of the electronic and steric effects that determine the stereochemical outcome of the reaction of Schiff bases with homophthalic …
M Cushman, EJ Madaj
文献索引：Cushman, Mark; Madaj, Edmund J. Journal of Organic Chemistry, 1987 , vol. 52, # 5 p. 907 - 915
A study has been undertaken of the electronic and steric effects that determine the ratios of cis-and trans-isoquinolones 9 formed in the condensation of para-substituted Schiff bases 8 with homophthalic anhydride (5). A linear correlation between the ratioe of the cis-and trans- isoquinolones formed and the Hammett u+ constants of the substituents in the aromatic ring has been observed. Electron-donating substituents have been found to favor formation of ...
