A highly selective space-folded photo-induced electron transfer fluorescent probe for carbonic anhydrase isozymes IX and its applications for biological imaging
Despite the fact that in the postgenomic and proteomic era a vast array of genetic and proteomic information has been revealed, opportunities and challenges exist for imaging to play a significant role in basic, translational and clinical research. Accordingly, the development of selective and sensitive imaging probes for biomacromolecules has emerged as a new frontier in biomedical research. 1,2 Notably, small-molecule fluorescent probes have been demonstrated as ...