A Safe Two-Step Process for Manufacturing Glycidyl Nitrate from Glycidol Involving Solid–Liquid Phase-Transfer Catalysis

…, JJ Blanco-Gómez

文献索引：Ochoa-Gomez, Jose R.; Blanco-Gomez, Juan J. Organic Process Research and Development, 2011 , vol. 15, # 6 p. 1454 - 1457

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被引用次数: 4

摘要

A new and safer two-step process for manufacturing glycidyl nitrate from glycidol is reported. In the first step glycidyl tosylate is obtained by reacting glycidol with p-tosyl chloride in the presence of triethylamine according to any one of the well-known procedures for obtaining tosyl esters described in the literature. In the second step, glycidyl tosylate is reacted with NaNO3 in refluxing acetonitrile under solid–liquid phase-transfer catalysis conditions ...