Synthesis of novel hypotensive aromatic thiocarbamate glycosides

R Saleem, J Meinwald

文献索引：Saleem, Rubeena; Meinwald, Jerrold Journal of the Chemical Society, Perkin Transactions 1, 2000 , # 3 p. 391 - 394

全文：HTML全文

被引用次数: 14

摘要

Syntheses of hypotensive thiocarbamate glycosides from Moringa oleifera are described. The route involves, first, the condensation of the sugar moiety with p-hydroxybenzonitrile to give glycoside 2, then subsequent reduction of 2 to the glycosidic benzylamine 3, which is then converted into isothiocyanate 6. Finally, alcoholysis of 6 gives the desired thiocarbamate glycosides.