Rational design, synthesis, and structure–activity relationship of benzoxazolones: New potent mglu5 receptor antagonists based on the fenobam structure

SM Ceccarelli, G Jaeschke, B Buettelmann…

文献索引：Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 5 p. 1302 - 1306

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被引用次数: 19

摘要

... Bioorganic & Medicinal Chemistry Letters. ... In this respect, the mGlu5 receptor appears to be an attractive target, due to the validated proof of concept 6 and the potential for selectivity and chemical tractability offered by the allosteric site. ...