In the course of an investigation of quinoline derivatives of potential antimalarial activity, certain aminolepidines were prepared from the corresponding nitro compounds. 2 It was found that the nitration of 2-chlorolepidine yielded two isomeric mono nitro derivatives in a ratio of 1: 6. The isomer formed in smaller amount was identified as G-nitro-2-chlorolepidinej while the major reaction product was postulated to be 5-nitro-2-chlorolepidine. The 8- ...
