A novel approach for the one-pot synthesis of linear and angular fused quinazolinones

…, S Naskar, KB Sahu, P Saha, S Banerjee, NB Mondal

文献索引：Maity, Arindam; Mondal, Shyamal; Paira, Rupankar; Hazra, Abhijit; Naskar, Subhendu; Sahu, Krishnendu B.; Saha, Pritam; Banerjee, Sukdeb; Mondal, Nirup B. Tetrahedron Letters, 2011 , vol. 52, # 23 p. 3033 - 3037

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被引用次数: 16

摘要

Abstract A convenient and inexpensive one step methodology has been developed for the synthesis of linear and angular fused quinazolinones. The protocol, which uses amino heterocycles and o-bromo benzyl/naphthyl bromides as reactants, CuI as catalyst, Cs 2 CO 3 as base, l-proline as ligand, and DMF as solvent, proceeds via nucleophilic aromatic substitution of the N-heteroaromatic cationic intermediate followed by in situ aerial ...