Radiolabeled antagonistic bombesin peptidomimetics for tumor targeting

IE Valverde, E Huxol, TL Mindt

文献索引：Valverde, Ibai E.; Huxol, Elena; Mindt, Thomas L. Journal of Labelled Compounds and Radiopharmaceuticals, 2014 , vol. 57, # 4 p. 275 - 278

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被引用次数: 4

摘要

The replacement of amide bonds in the backbone of peptides by proteolytically stable 1, 2, 3- triazole isosteres can provide novel peptidomimetics with promising properties for the development of tumor-targeting radiopeptides. On the basis of our previous work with radiolabeled agonistic bombesin (BBN) derivatives of the sequence [Nle14] BBN (7–14), we substituted selected amide bonds of the structurally closely related antagonistic peptide ...