Coupling of ribofuranosyl fluoride and indoles

M Yokoyama, M Nomura, H Togo, H Seki

文献索引：Yokoyama, Masataka; Nomura, Mitsuru; Togo, Hideo; Seki, Hiroko Journal of the Chemical Society - Perkin Transactions 1, 1996 , # 17 p. 2145 - 2149

全文：HTML全文

被引用次数: 26

摘要

The coupling reaction of a D-ribofuranosyl fluoride with indoles in the presence of boron trifluoride gives the corresponding C-nucleosides in a stereoselective manner depending upon reaction temperatures and solvents: the β-anomer is preferred under such conditions as–15 to–40° C in nitroethane while the α-anomer is preferred at–78° C in propiononitrile.