Regioselective nucleophilic 1, 4-trifluoromethylation of 2-polyfluoroalkylchromones with (trifluoromethyl) trimethylsilane. Synthesis of fluorinated analogs of natural 2, 2 …
VY Sosnovskikh, BI Usachev…
文献索引：Sosnovskikh; Usachev Russian Chemical Bulletin, 2001 , vol. 50, # 3 p. 453 - 455
Reactions of 2-polyfluoroalkylchromones with (perfluoroalkyl) trimethylsilanes proceed as a 1, 4-nucleophilic perfluoroalkylation to give 2, 2-bis (polyfluoroalkyl) chroman-4-ones with high regioselectivity and good yields after acid hydrolysis. Oxidation of 6-methyl-2, 2-bis
