Polyanion inhibitors of human immunodeficiency virus and other viruses. 5. Telomerized anionic surfactants derived from amino acids

…, J Este, R Snoeck, G Andrei, E De Clercq

文献索引：Leydet, Alain; Barragan, Veronique; Boyer, Bernard; Montero, Jean Louis; Roque, Jean Pierre; Witvrouw, Myriam; Este, Jose; Snoeck, Robert; Andrei, Graciela; De Clercq, Erick Journal of Medicinal Chemistry, 1997 , vol. 40, # 3 p. 342 - 349

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被引用次数: 17

摘要

ω-Acryloyl anionic surfactants, whose polar heads are derived from amino acids, have been telomerized to prepare polyanions of a predetermined molecular weight. The main goal of this study was to verify whether the antiviral activity is influenced by the degree of polymerization of the polyanions. The oligomeric polyanions were evaluated for their activity against human immunodeficiency virus (HIV-1 or HIV-2) and various other RNA and DNA ...