2-(2-furyl) imidazo [1, 2-a] pyrimidine synthesis and electrophilic substitution reactions

N Saldabol, J Popelis, O Lando, V Slavinska

文献索引：Saldabol; Popelis; Lando; Slavinska Chemistry of Heterocyclic Compounds, 2006 , vol. 42, # 4 p. 495 - 499

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被引用次数: 1

摘要

Abstract The synthesis of 2-(2-furyl) imidazo [1, 2-a] pyrimidine has been carried out. Azocoupling, nitrosation, and bromination by 1 mole of bromine occur at position 3 of the bicycle. Reaction with 2 mol of bromine gives the 3, 5‰-disubstituted derivative. Bromination using 1 mol of bromine in 40% hydrobromic acid and sulfonation occur initially at the 5‰ position of the furyl group.