Tetrahedron

Approaching ambient temperatures in 1, 2-DCE to deliver efficient intermolecular Dötz benzannulation processes

S Irvine, WJ Kerr, AR McPherson, CM Pearson

文献索引：Irvine, Stephanie; Kerr, William J.; McPherson, Allan R.; Pearson, Colin M. Tetrahedron, 2008 , vol. 64, # 5 p. 926 - 935

全文：HTML全文

被引用次数: 10

摘要

Conditions have been developed that enable intermolecular Dötz benzannulations to be carried out under extremely mild conditions, using 1, 2-DCE as the reaction solvent and without the requirement for any additional reaction promoters. The new protocols, at temperatures close to ambient, have been applied successfully to a range of internal and terminal alkynes with a series of aryl and alkenyl carbene complexes, resulting in good to ...