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Novel transient receptor potential vanilloid 1 receptor antagonists for the treatment of pain: structure-activity relationships for ureas with quinoline, isoquinoline, …

A Gomtsyan, EK Bayburt, RG Schmidt…

文献索引:Journal of Medicinal Chemistry, , vol. 48, # 3 p. 744 - 752

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被引用次数: 127

摘要

... Journal of Medicinal Chemistry. ... Chemistry. The compounds 5, 6, and 7 (Scheme 1) with 5- and 8-quinoline as well as 5-isoquinoline moieties were prepared by acylation of corresponding commercially available amines ...