Synthesis

Reduction of esters to ethers utilizing the powerful lewis acid BF2OTf· OEt2

NA Morra, BL Pagenkopf

文献索引：Morra, Nicholas A.; Pagenkopf, Brian L. Synthesis, 2008 , # 4 p. 511 - 514

被引用次数: 4

摘要

Abstract The direct reduction of esters to their corresponding ethers has been achieved using the Lewis acid BF 2 OTf· OEt 2 generated via anionic redistribution between TMSOTf and BF 3· OEt 2 with triethylsilane acting as the reducing agent. Isolated yields of up to 71% have been obtained with the corresponding alcohol as the only side product.

~9%

详细

~6%

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~3%

详细

~3%

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~6%

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~73%

~66%

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~63%

~46%

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