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Synthesis and SAR of 6-chloro-4-fluoroalkylamino-2-heteroaryl-5-(substituted) phenylpyrimidines as anti-cancer agents

N Zhang, S Ayral-Kaloustian, T Nguyen…

文献索引:Bioorganic and Medicinal Chemistry, , vol. 17, # 1 p. 111 - 118

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被引用次数: 20

摘要

... Please enable JavaScript to use all the features on this page. Bioorganic & Medicinal Chemistry. ... 2). The compound was selected to advance to preclinical development, based on its pharmaceutical properties and efficacies in in vivo xenograft studies. ...