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Tetrahedron letters

Observations on the intramolecular Heck reactions of aromatic chlorides using palladium/imidazolium salts

S Caddick, W Kofie

文献索引:Caddick, Stephen; Kofie, William Tetrahedron Letters, 2002 , vol. 43, # 51 p. 9347 - 9350

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被引用次数: 61

摘要

The intramolecular Heck reaction of aromatic amines and ethers using palladium/imidazolium salts is described. The use of tetra-n-butylammonium halide salts facilitates the reactivity of aromatic chlorides. An unexpected and novel palladium-mediated cyclisation is also described leading to the formation of a tricyclic adduct.