Syntheses and Reactions of 1??Amino??2, 2??dialkylcyclopropane??1??carbonitriles and??carboxamides–Potential Precursors of ACC Derivatives

…, W Coppens, T Huybrechts, N De Kimpe…

文献索引：Aelterman, Wim; Tehrani, Kourosch Abbaspour; Coppens, Wim; Huybrechts, Tom; De Kimpe, Norbert; Tourwe, Dirk; Declercq, Jean-Paul European Journal of Organic Chemistry, 1999 , # 1 p. 239 - 250

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被引用次数: 10

摘要

Abstract The direct cyclization of 2-amino-4-chloro-3, 3-dimethylbutanenitrile with potassium tert-butoxide in THF afforded 1-amino-2, 2-dimethylcyclopropane-1-carbonitrile and a dimerization product. Various new cis-and trans-1-(tert-butylamino)-2-benzyl-2- methylcyclopropane-carbonitriles and© the corresponding cyclopropanecarboxamides have been synthesized, with focus on the isolation of the pure stereoisomeric ...