The Journal of Organic Chemistry

A short and facile synthetic route to hydroxylated flavones. New syntheses of apigenin, tricin, and luteolin

D Nagarathnam, M Cushman

文献索引：Nagarathnam, Dhanapalan; Cushman, Mark Journal of Organic Chemistry, 1991 , vol. 56, # 16 p. 4884 - 4887

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被引用次数: 47

摘要

Ring-A hydroxylated flavones are of current interest due to biological activities including inhibition of retroviral reverse transcriptase^,^-^ protein-tyrosine kinases, b6 and serine/threonine kinases.'They possess anticance#*'and chemopreventative activities? and certain ring-A hydroxylated flavones inhibit HIV-induced syncytium formation? Although a number of methods are available for the synthesis of flavones,* 18 they are not ideal for ...