Discovery of inducible nitric oxide synthase (iNOS) inhibitor development candidate KD7332, part 1: Identification of a novel, potent, and selective series of …

C Bonnefous, JE Payne, J Roppe…

文献索引：Journal of Medicinal Chemistry, , vol. 52, # 9 p. 3047 - 3062

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被引用次数: 47

摘要

... Journal of Medicinal Chemistry. ... There has been substantial activity in the pharmaceutical industry to identify selective iNOS inhibitors, with selectivity over eNOS being particularly important as inhibition can result in an elevation of blood pressure. ...