Tetrahedron letters

Direct access to functionalised allylsilanes: The cerium (III) mediated grignard reaction of functionalised esters and lactones.

TV Lee, JR Porter, FS Roden

文献索引：Lee, Thomas V.; Porter, John R.; Roden, Frances S. Tetrahedron Letters, 1988 , vol. 29, # 39 p. 5009 - 5012

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被引用次数: 18

摘要

Abstract The use of cerium (III) chloride alters the chemoselectivity of the reaction of the Grignard reagent (1) with ester-acetals and also greatly improves the efficiency of reaction with lactones. In addition it gives improved preparations of the useful intermediates (8),(11) and (12) giving direct access to valuable functionalised allylsilanes of use in annulation reactions.