Organic letters

New Synthetic Technology for Efficient Construction of α-Hydroxy-β-amino Amides via the Passerini Reaction1

JE Semple, TD Owens, K Nguyen, OE Levy

文献索引：Organic Letters, , vol. 2, # 18 p. 2769 - 2772

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被引用次数: 110

摘要

... Volume: Page: Digital Object Identifier (DOI). ... Organic Letters. ... Using the formation of intermediate 7o from allyl isocyanoacetate and N-α-Fmoc-nVal-H as a model reaction, we surveyed a variety of organic bases whose pK a values ranged from 5 to 11. ...